Virus-Host Cell Interplay in Cancer Progression by Fang Cheng
--------------------------------------------------------------- Author: Fang Cheng Number of Pages: 140 pages Published Date: 24 Apr 2012 Publisher: LAP Lambert Academic Publishing Publication Country: Germany Language: English ISBN: 9783659105159 File size: 23 Mb File Name: virus-host.cell.interplay.in.cancer.progression.pdf Download Link: virus-host cell interplay in cancer progression --------------------------------------------------------------- Human tumor viruses contribute to 15-20% of human cancers worldwide. Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma (KS) and two other malignancies. KS is the most common cancer in HIV-infected untreated individuals and remains a primary cause of cancer deaths in many subequatorial African countries as a result of the AIDS pandemic. This book first introduces an unbiased gain-of-function human kinome cDNA screen on KSHV reactivation in infected human cells. By developing a novel 3D cell culture model reflecting the context of virus-host cell interaction, this book further reveals the first lymphatic-specific endothelial-to-mesenchymal transition (EndMT) induced by a human tumor virus, giving rise to infected, invasive cells, and providing the virus a permissive cellular microenvironment for efficient spread of the virus. This book should shed lights on understanding the long-term persistence of oncogenic infectious agents in infected individuals, allowing time for the multi-step tumorigenesis. It should also be especially useful for professionals who are interested in developing targeted therapies to prevent or at least slow down KS progression. Read online Virus-Host Cell Interplay in Cancer Progression Buy and read online Virus-Host Cell Interplay in Cancer Progression Download and read Virus-Host Cell Interplay in Cancer Progression for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook Virus-Host Cell Interplay in Cancer Progression Other entries: Winnie the Witch Six Book and Two CD Collection download torrentbest free keygen software
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